| # | % | |||||
|---|---|---|---|---|---|---|
| 101 | SIENTRA INC | 2,413 | 2,056,000 | 0.12% | Put | |
| 102 | DURECT CORP | 1,528,516 | 2,048,000 | 0.12% | ||
| 103 | REDHILL BIOPHARMA LTD | 191,785 | 2,006,000 | 0.12% | ||
| 104 | ARBUTUS BIOPHARMA CORP | 792,617 | 1,942,000 | 0.11% | ||
| 105 | INSMED INC | 1,459 | 1,930,000 | 0.11% | Call | |
| 106 | SANGAMO THERAPEUTICS INC | 6,177 | 1,884,000 | 0.11% | Call | |
| 107 | CLOVIS ONCOLOGY INC | 420 | 1,866,000 | 0.11% | Put | |
| 108 | EDITAS MEDICINE INCORPORATED | 115,000 | 1,866,000 | 0.11% | ||
| 109 | Pieris Pharmaceuticals | 1,296,034 | 1,814,000 | 0.11% | ||
| 110 | OPKO HEALTH INC | 190,955 | 1,776,000 | 0.10% | ||
| 111 | WAFERGEN BIO-SYSTEMS INC | 358,535 | 1,771,000 | 0.10% | ||
| 112 | CYTRX CORP | 4,697,802 | 1,749,000 | 0.10% | ||
| 113 | BARCLAYS BK PLC | 50,000 | 1,743,000 | 0.10% | ||
| 114 | OHR PHARMACEUTICAL INC | 1,156,393 | 1,735,000 | 0.10% | ||
| 115 | INTELLIA THERAPEUTICS INC | 130,000 | 1,704,000 | 0.10% | ||
| 116 | PARATEK PHARMACEUTICALS INC | 110,000 | 1,694,000 | 0.10% | ||
| 117 | SAREPTA THERAPEUTICS INC | 611 | 1,676,000 | 0.10% | Call | |
| 118 | NEWLINK GENETICS CORP | 1,580 | 1,624,000 | 0.09% | Call | |
| 119 | EXPRESS SCRIPTS HLDG CO | 23,494 | 1,616,000 | 0.09% | ||
| 120 | ACADIA PHARMACEUTICALS INC | 548 | 1,580,000 | 0.09% | Put | |
| 121 | HISTOGENICS CORP | 944,891 | 1,578,000 | 0.09% | ||
| 122 | LION BIOTECHNOLOGIES INC COM | 226,081 | 1,571,000 | 0.09% | ||
| 123 | FORWARD PHARMA A/S | 104,273 | 1,565,000 | 0.09% | ||
| 124 | MEDICINES CO | 457 | 1,551,000 | 0.09% | Call | |
| 125 | ROKA BIOSCIENCE INC COM NEW | 365,220 | 1,549,000 | 0.09% | ||
| 126 | VERACYTE INC | 193,999 | 1,502,000 | 0.09% | ||
| 127 | OncoSec Medical Inc | 1,173,946 | 1,444,000 | 0.08% | ||
| 128 | AETERNA ZENTARIS INC | 400,560 | 1,442,000 | 0.08% | ||
| 129 | Sierra Oncology, Inc. | 940,841 | 1,402,000 | 0.08% | ||
| 130 | SOPHIRIS BIO INC | 496,729 | 1,391,000 | 0.08% | ||
| 131 | OPKO HEALTH INC | 1,491 | 1,387,000 | 0.08% | Call | |
| 132 | CHECK CAP LTD | 575,113 | 1,352,000 | 0.08% | ||
| 133 | KITE PHARMA INC | 291 | 1,305,000 | 0.08% | Put | |
| 134 | Axovant Sciences LTD | 100,998 | 1,254,000 | 0.07% | ||
| 135 | BIODELIVERY SCIENCES INTL IN | 698,235 | 1,222,000 | 0.07% | ||
| 136 | CARDIOME PHARMA CORP | 437,720 | 1,208,000 | 0.07% | ||
| 137 | NEVRO CORP | 165 | 1,199,000 | 0.07% | Call | |
| 138 | GENETIC TECHNOLOGIES LTD | 1,070,333 | 1,156,000 | 0.07% | ||
| 139 | APPLIED DNA SCIENCES INC | 2,277,612 | 1,139,000 | 0.07% | ||
| 140 | REXAHN PHARMACEUTICALS INC | 7,326,681 | 1,040,000 | 0.06% | ||
| 141 | IGNYTA INC COM | 195,000 | 1,034,000 | 0.06% | ||
| 142 | AGENUS INC | 2,503 | 1,031,000 | 0.06% | Put | |
| 143 | ONCONOVA THERAPEUTICS INC | 452,804 | 1,028,000 | 0.06% | ||
| 144 | SUCAMPO PHARMACEUTICALS INCORPORATED CLASS A | 75,000 | 1,016,000 | 0.06% | ||
| 145 | CAPRICOR THERAPEUTICS INC | 372,046 | 990,000 | 0.06% | ||
| 146 | ZAFGEN INC COM | 310,000 | 986,000 | 0.06% | ||
| 147 | FOAMIX PHARMACEUTICALS LTD | 881 | 978,000 | 0.06% | Call | |
| 148 | LEXICON PHARMACEUTICALS INC | 70,040 | 969,000 | 0.06% | ||
| 149 | HEMISPHERX BIOPHARMA INC | 1,391,286 | 960,000 | 0.06% | ||
| 150 | DURECT CORP | 6,927 | 928,000 | 0.05% | Call |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-17-008083, filed 2017.02.14).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
