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Institutional Investment Manager
BAKER BROS. ADVISORS LP
BAKER BROS. ADVISORS LP (CIK: 0001263508) incorporated in Delaware, located at 860 Washington Street, New York, NY. Institutional holdings reported to the SEC.

Institutional Holdings (2015Q2)
Portfolio Summary: 126 holdings with a total value of $11,400,413,000.
#
Name
Shares
Value ($)
%
Options
Notes
101 VERSARTIS INC 3,436,585 52,305,000 0.46%
102 DBV TECHNOLOGIES S A 1,862,019 55,451,000 0.49%
103 XOMA CORP DEL 14,683,513 56,972,000 0.50%
104 ACORDA THERAPEUTICS INC 59,583,000 60,049,000 0.53% PRN
105 CERUS CORP 13,553,275 70,341,000 0.62%
106 Medivation Inc 04/01/2017 2.625% 33,889,000 75,011,000 0.66% PRN
107 SPARK THERAPEUTICS INCORPORATED 1,262,382 76,084,000 0.67%
108 HERON THERAPEUTICS INC COM 2,807,784 87,491,000 0.77%
109 MIRATI THERAPEUTICS INC COM 2,805,074 88,276,000 0.77%
110 BELLICUM PHARMACEUTICALS INCORPORATED 4,190,594 89,134,000 0.78%
111 INVITAE CORP 6,554,967 97,538,000 0.86%
112 GILEAD SCIENCES 20,944,000 107,926,000 0.95% PRN
113 BIOMARIN PHARMACEUTICAL INC SR SB CV1.875 17 22,379,000 149,970,000 1.32% PRN
114 BIOCRYST PHARMACEUTICALS 11,577,299 172,849,000 1.52%
115 DYAX CORP COM CVR 7,926,630 210,056,000 1.84%
116 Anacor Pharmaceuticals Inc 3,625,498 280,722,000 2.46%
117 GENOMIC HEALTH INC COM 13,657,598 379,545,000 3.33%
118 INCYTE CORP SR NT CONV 4.750% 10/01/15 B/EDTD 03/30/10 0221 UBS FINANCIAL SERVICES INC. A/C MR06471 40,446,000 478,833,000 4.20% PRN
119 Incyte Corporation 259,000,000 529,519,000 4.64% PRN
120 BIOMARIN PHARMACEUTICAL INC 4,095,247 560,148,000 4.91%
121 Incyte Corporation 274,500,000 567,758,000 4.98% PRN
122 ACADIA PHARMACEUTICALS INC COM 20,481,442 857,763,000 7.52%
123 ABBVIE INC 14,373,538 965,758,000 8.47%
124 ALEXION PHARMACEUTIC 6,542,599 1,182,706,000 10.37%
125 SEATTLE GENETICS INC 30,870,262 1,494,121,000 13.11%
126 INCYTE CORP 14,865,559 1,549,140,000 13.59%
Page 3 of 3

Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-15-049845, filed 2015.08.14).

From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.