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Institutional Investment Manager
BAKER BROS. ADVISORS LP
BAKER BROS. ADVISORS LP (CIK: 0001263508) incorporated in Delaware, located at 860 Washington Street, New York, NY. Institutional holdings reported to the SEC.

Institutional Holdings (2015Q2)
Portfolio Summary: 126 holdings with a total value of $11,400,413,000.
#
Name
Shares
Value ($)
%
Options
Notes
101 AURINIA PHARMACEUTICALS INC 711,499 2,130,000 0.02%
102 IRONWOOD PHARMACEUTICALS INC 169,163 2,040,000 0.02%
103 OPHTHOTECH CORP 35,649 1,856,000 0.02%
104 ADAPTIMMUNE THERAPEUTICS PLC 100,000 1,833,000 0.02%
105 PALATIN TECHNOLOGIES INC COM 2,050,000 1,825,000 0.02%
106 CELLECTIS S A 50,000 1,804,000 0.02%
107 LOXO ONCOLOGY INC COM 100,000 1,803,000 0.02%
108 RITTER PHARMACEUTICALS INC 400,000 1,780,000 0.02%
109 Ascendis Pharma 100,000 1,768,000 0.02%
110 DERMIRA INC COM 100,000 1,755,000 0.02%
111 BIOTA PHARMACEUTIALS INC COM 830,440 1,719,000 0.02%
112 BIODELIVERY SCIENCES INTL IN 210,021 1,672,000 0.01%
113 MEDIWOUND ORD 225,000 1,591,000 0.01%
114 ALNYLAM PHARMACEUTICALS INC 11,340 1,359,000 0.01%
115 TENAX THERAPEUTICS INC 355,348 1,311,000 0.01%
116 Aldeyra Therapeutics Inc 142,000 1,102,000 0.01%
117 OHR PHARMACEUTICAL INC 370,370 930,000 0.01%
118 ACCELERON PHARMA INC 28,765 910,000 0.01%
119 UNIQURE NV 30,000 810,000 0.01%
120 Foundation Medicine 20,892 707,000 0.01%
121 ACHAOGEN INC COM 100,000 603,000 0.01%
122 FIVE PRIME THERAPEUTICS INC 19,247 478,000 0.00%
123 CHEMOCENTRYX INC 49,064 404,000 0.00%
124 APTOSE BIOSCIENCES INC 33,397 170,000 0.00%
125 CYCLACEL PHARMACEUTICALS INC 13,253 85,000 0.00%
126 BIOTIME INC 20,084 23,000 0.00%
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Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-15-049845, filed 2015.08.14).

From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.