| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | GILEAD SCIENCES INC | 1,782,298 | 180,351,000 | 7.69% | ||
| 2 | ALEXION PHARMACEUTIC | 758,180 | 144,623,000 | 6.17% | ||
| 3 | BIOMARIN | 1,359,922 | 142,465,000 | 6.07% | ||
| 4 | CELGENE CORP | 1,177,058 | 140,964,000 | 6.01% | ||
| 5 | REGENERON PHARMACEUTICALS | 236,300 | 128,280,000 | 5.47% | ||
| 6 | INCYTE | 1,127,423 | 122,269,000 | 5.21% | ||
| 7 | BIOGEN INC | 290,889 | 89,114,000 | 3.80% | ||
| 8 | VERTEX PHARMACEUT | 688,200 | 86,596,000 | 3.69% | ||
| 9 | THERMO FISHER SCIENTIFIC INC | 606,936 | 86,094,000 | 3.67% | ||
| 10 | AMGEN INC | 504,597 | 81,911,000 | 3.49% | ||
| 11 | AMICUS THERAPEUTICS INC | 7,973,436 | 77,342,000 | 3.30% | ||
| 12 | MERCK & CO INC | 1,121,925 | 59,260,000 | 2.53% | ||
| 13 | SEATTLE GENETICS INC | 1,275,775 | 57,257,000 | 2.44% | ||
| 14 | ACCELERON PHARMA | 1,121,264 | 54,673,000 | 2.33% | ||
| 15 | PTC THERAPEUTICS INC | 1,586,258 | 51,395,000 | 2.19% | ||
| 16 | LILLY ELI & CO | 599,245 | 50,492,000 | 2.15% | ||
| 17 | MEDTRONIC PLC | 543,792 | 41,828,000 | 1.78% | ||
| 18 | TEVA PHARMACEUTICAL INDS LTD | 605,922 | 39,773,000 | 1.70% | ||
| 19 | HALOZYME THERAPEUTICS INC | 2,075,796 | 35,974,000 | 1.53% | ||
| 20 | SHIRE PLC | 164,674 | 33,758,000 | 1.44% | ||
| 21 | INTERCEPT PHARMACEUTICAL | 220,047 | 32,864,000 | 1.40% | ||
| 22 | MYLAN N V | 601,910 | 32,545,000 | 1.39% | ||
| 23 | ALDER BIOPHARMACEUTICALS INC | 934,951 | 30,881,000 | 1.32% | ||
| 24 | UNITED THERAPEUTICS | 195,280 | 30,583,000 | 1.30% | ||
| 25 | DEXCOM | 362,733 | 29,708,000 | 1.27% | ||
| 26 | ALIGN TECHNOLOGY INC | 386,104 | 25,425,000 | 1.08% | ||
| 27 | UNITEDHEALTH GROUP INC | 209,648 | 24,663,000 | 1.05% | ||
| 28 | ST JUDE | 397,161 | 24,533,000 | 1.05% | ||
| 29 | NEUROCRINE BIOSCIE COM USD0.001 | 416,680 | 23,572,000 | 1.01% | ||
| 30 | OPHTHOTECH CORP COM | 288,906 | 22,688,000 | 0.97% | ||
| 31 | TESARO INC | 405,069 | 21,193,000 | 0.90% | ||
| 32 | CARA THERAPEUTICS INC | 1,212,578 | 20,444,000 | 0.87% | ||
| 33 | EDWARDS LIFESCIENCES CORP | 250,295 | 19,768,000 | 0.84% | ||
| 34 | UNIQURE NV | 1,138,513 | 18,831,000 | 0.80% | ||
| 35 | TG THERAPEUTICS INC COM | 1,521,667 | 18,153,000 | 0.77% | ||
| 36 | AIMMUNE THERAPEUTICS INC COM | 982,133 | 18,120,000 | 0.77% | ||
| 37 | ADVAXIS INC COM NEW | 1,790,715 | 18,015,000 | 0.77% | ||
| 38 | IMMUNE DESIGN CORP COM | 856,867 | 17,206,000 | 0.73% | ||
| 39 | INTUITIVE SURGICAL INC | 31,030 | 16,947,000 | 0.72% | ||
| 40 | NOVO-NORDISK A S | 277,075 | 16,093,000 | 0.69% | ||
| 41 | NXSTAGE MED INC COM | 701,303 | 15,366,000 | 0.66% | ||
| 42 | NOVARTIS A G | 178,405 | 15,350,000 | 0.65% | ||
| 43 | ProNAi Therapeutics, Inc. | 910,566 | 14,386,000 | 0.61% | ||
| 44 | SAGENT PHARMACEUTICALS INC | 810,362 | 12,893,000 | 0.55% | ||
| 45 | Teladoc, Inc. | 577,361 | 10,369,000 | 0.44% | ||
| 46 | Heartware International, Inc. | 204,008 | 10,282,000 | 0.44% | ||
| 47 | Adeptus Health Inc | 187,744 | 10,236,000 | 0.44% | ||
| 48 | ACADIA HEALTHCARE COMPANY IN | 158,852 | 9,922,000 | 0.42% | ||
| 49 | IONIS PHARMACEUTICALS INC | 150,000 | 9,290,000 | 0.40% | ||
| 50 | CIGNA CORPORATION | 57,104 | 8,356,000 | 0.36% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001104659-16-096363, filed 2016.02.12).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
