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Institutional Investment Manager
BAKER BROS. ADVISORS LP
BAKER BROS. ADVISORS LP (CIK: 0001263508) incorporated in Delaware, located at 860 Washington Street, New York, NY. Institutional holdings reported to the SEC.

Institutional Holdings (2016Q3)
Portfolio Summary: 134 holdings with a total value of $11,019,928,000.
#
Name
Shares
Value ($)
%
Options
Notes
101 OPHTHOTECH CORP 35,649 1,644,000 0.01%
102 MYOKARDIA INC 100,000 1,634,000 0.01%
103 SERES THERAPEUTICS INC 125,000 1,536,000 0.01%
104 PALATIN TECHNOLOGIES INC COM 2,050,000 1,289,000 0.01%
105 CELLECTIS S A 50,000 1,204,000 0.01%
106 COLUCID PHARMACEUTICALS ORD 30,310 1,156,000 0.01%
107 FULGENT GENETICS INC 125,000 1,153,000 0.01%
108 IMMUNE DESIGN CORP 148,937 1,129,000 0.01%
109 AFFIMED N V COM 400,000 1,112,000 0.01%
110 Aldeyra Therapeutics Inc 142,000 1,110,000 0.01%
111 ACCELERON PHARMA INC 28,765 1,041,000 0.01%
112 FIVE PRIME THERAPEUTICS INC 19,247 1,010,000 0.01%
113 TENAX THERAPEUTICS INC 420,000 972,000 0.01%
114 MAST THERAPEUTICS INC COM 8,584,051 944,000 0.01%
115 APTOSE BIOSCIENCES INC 404,211 909,000 0.01%
116 INFINITY PHARMACEUTICALS INC 580,400 905,000 0.01%
117 DYNAVAX TECHNOLOGIES CORP 75,000 787,000 0.01%
118 ALNYLAM PHARMACEUTICALS INC 11,340 769,000 0.01%
119 MADRIGAL PHARMACEUTICALS INC 57,762 732,000 0.01%
120 ADAPTIMMUNE THERAPEUTICS PLC 100,000 705,000 0.01%
121 RITTER PHARMACEUTICALS INC 400,000 672,000 0.01%
122 WINDTREE THERAPEUTICS INC 254,973 653,000 0.01%
123 CHIMERIX INC 115,216 638,000 0.01%
124 ARBUTUS BIOPHARMA CORP 180,582 621,000 0.01%
125 ABEONA THERAPEUTICS INC 101,680 610,000 0.01%
126 BIODELIVERY SCIENCES INTL IN 210,021 567,000 0.01%
127 Foundation Medicine 20,892 488,000 0.00%
128 ACHAOGEN INC COM 100,000 479,000 0.00%
129 CYTRX CORP 659,995 388,000 0.00%
130 Sierra Oncology, Inc. 200,000 364,000 0.00%
131 LA JOLLA PHARMACEUTICAL CO 13,746 327,000 0.00%
132 CHEMOCENTRYX INC 49,064 296,000 0.00%
133 CYCLACEL PHARMACEUTICALS INC 13,253 90,000 0.00%
134 BIOTIME INC 20,084 17,000 0.00%
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Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-16-134352, filed 2016.11.14).

From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.