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Institutional Investment Manager
DAFNA Capital Management LLC
DAFNA Capital Management LLC (CIK: 0001389933), located at 10990 Wilshire Boulevard, Los Angeles, CA. Institutional holdings reported to the SEC.

Institutional Holdings (2015Q1)
Portfolio Summary: 71 holdings with a total value of $130,246,000.
#
Name
Shares
Value ($)
%
Options
Notes
1 OPEXA THERAPEUTICS EQUITY WARRANTS 03/13/201 500 0 0.00%
2 CHECK CAP LTD 55,000 55,000 0.04%
3 GLOBEIMMUNE INC 9,445 69,000 0.05% SH
4 TONIX PHARMACEUTICALS HOLDING 14,400 91,000 0.07% SH
5 FATE THERAPEUTICS INC 20,190 99,000 0.08% SH
6 CHEMBIO DIAGNOSTICS INC COM NEW 26,287 106,000 0.08% SH
7 APTOSE BIOSCIENCES INC 22,289 121,000 0.09%
8 CAS MED SYS INC 100,000 134,000 0.10%
9 NANOSPHERE INC 600,000 139,000 0.11% SH
10 TRANSITION THERAPEUTICS INC 26,410 180,000 0.14%
11 ACTINIUM PHARMACEUTICALS INC 90,000 222,000 0.17%
12 BOVIE MEDICAL CORP COM 100,000 239,000 0.18%
13 LPATH INC 111,884 276,000 0.21% SH
14 GENVEC INC 100,000 295,000 0.23% SH
15 CUTERA INC COM 23,490 303,000 0.23% SH
16 VENAXIS INC 658,000 305,000 0.23% SH
17 GALENA BIOPHARMA INC 250,000 348,000 0.27%
18 Aldeyra Therapeutics Inc 35,000 356,000 0.27%
19 LUMENIS LTD 31,072 372,000 0.29% SH
20 EPIZYME INC COM 20,000 376,000 0.29%
21 AFFIMED N V COM 62,500 394,000 0.30% SH
22 RTI SURGICAL HOLDINGS INC COM 85,918 424,000 0.33% SH
23 KERYX BIOPHARMACEUTICALS INCORPORATED 34,800 443,000 0.34% SH
24 MINERVA NEUROSCIENCES INC COM 101,317 507,000 0.39%
25 CYNAPSUS THERAPEUTICS INC 543,927 521,000 0.40% SH
26 INTERCEPT PHARMACEUTICALS INCORPORATED 2,000 564,000 0.43% SH
27 COGENTIX MED INC 353,181 593,000 0.46%
28 CHECK CAP LTD 110,000 605,000 0.46%
29 Cynapsus Therapeutics Inc 717,200 687,000 0.53%
30 CAREDX INC 123,883 687,000 0.53% SH
31 Curis, Inc 299,800 720,000 0.55% SH
32 UNIQURE NV 30,000 730,000 0.56% SH
33 Exactech Inc 31,636 811,000 0.62% SH
34 XENOPORT INC 116,259 828,000 0.64% SH
35 ENCISION INC 1,062,500 829,000 0.64% SH
36 NUVASIVE INC 760,000 935,000 0.72% PRN
37 CARDICA INC 1,486,004 936,000 0.72% SH
38 JOHNSON & JOHNSON 9,400 946,000 0.73% SH
39 TANDEM DIABETES CARE INC COM 76,340 963,000 0.74%
40 BLUEBIRD BIO INC COM 8,000 966,000 0.74% SH
41 CYTRX CORP 300,813 1,014,000 0.78% SH
42 SYNERON MEDICAL LTD 90,947 1,126,000 0.86% SH
43 ZOGENIX INC 853,700 1,170,000 0.90%
44 TARGACEPT INC 465,293 1,382,000 1.06% SH
45 SPECTRANETICS CORP 39,812 1,384,000 1.06% SH
46 ESSA Pharma 250,000 1,422,000 1.09%
47 BIOCRYST PHARMACEUTICALS 166,656 1,505,000 1.16% SH
48 Neothetics Inc 186,807 1,534,000 1.18% SH
49 Ascendis Pharma 93,541 1,623,000 1.25%
50 ZS PHARMA INC 39,100 1,645,000 1.26%
Page 1 of 2

Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001389933-15-000013, filed 2015.05.15).

From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.