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Institutional Investment Manager
DEERFIELD MANAGEMENT COMPANY, L.P.
DEERFIELD MANAGEMENT COMPANY, L.P. (CIK: 0001009258) incorporated in Delaware, located at 345 Park Avenue South, 12th Floor, New York, NY. Institutional holdings reported to the SEC.

Institutional Holdings (2015Q3)
Portfolio Summary: 134 holdings with a total value of $2,585,133,000.
#
Name
Shares
Value ($)
%
Options
Notes
51 LOXO ONCOLOGY INC COM 1,088,225 19,022,000 0.74%
52 GALAPAGOS NV 441,085 17,957,000 0.69%
53 ZAFGEN INC COM 553,472 17,683,000 0.68%
54 Proteon Therapeutics Inc 1,265,343 17,601,000 0.68%
55 DBV TECHNOLOGIES S A 461,869 16,438,000 0.64%
56 SYNERON MEDICAL LTD 2,079,013 14,865,000 0.58%
57 AERIE PHARMACEUTICALS INC COM 807,875 14,332,000 0.55%
58 NANOSTRING TECHNOLOGIES INC 880,622 14,090,000 0.55%
59 PORTOLA PHARMACEUTICALS INC 329,837 14,058,000 0.54%
60 AXOGEN INC 3,381,439 13,932,000 0.54%
61 EDWARDS LIFESCIENCES CORP 97,119 13,807,000 0.53%
62 ZELTIQ AESTHETICS INC 420,063 13,455,000 0.52%
63 NUVASIVE INC 265,272 12,791,000 0.49%
64 BROOKDALE SR LIVING INC 557,000 12,789,000 0.49%
65 ORTHOFIX INTL N V 360,459 12,165,000 0.47%
66 XENOPORT INC 3,445,374 11,955,000 0.46%
67 MACROGENICS INC 557,000 11,931,000 0.46%
68 TRUPANION INC 1,578,925 11,921,000 0.46%
69 ESSA Pharma 1,859,282 11,580,000 0.45%
70 ACHILLION PHARMACEUTICALS IN 1,667,000 11,519,000 0.45%
71 ALIMERA SCIENCES INC 4,420,580 9,769,000 0.38%
72 NEOS THERAPEUTICS INC COM 458,332 9,630,000 0.37%
73 GENESIS HEALTHCARE INC 1,538,232 9,429,000 0.36%
74 Arena Pharmaceuticals, Inc 4,640,877 8,864,000 0.34%
75 PACIFIC BIOSCIENCES CALIF IN 2,185,771 8,000,000 0.31%
76 NOVAVAX INC COM 1,040,000 7,353,000 0.28%
77 Heartware International, Inc. 134,200 7,020,000 0.27%
78 Oxford Immunotec Global PLC 519,670 7,016,000 0.27%
79 TONIX PHARMACEUTICALS HOLDING 1,315,551 6,959,000 0.27%
80 FOAMIX PHARMACEUTICALS LTD 948,934 6,956,000 0.27%
81 Egalet Corp 477,123 6,288,000 0.24%
82 Axovant Sciences LTD 484,664 6,262,000 0.24%
83 ALCOBRA LTD 997,349 6,024,000 0.23%
84 RIGEL PHARMACEUTICAL INC 2,397,855 5,923,000 0.23%
85 ALLIQUA BIOMEDICAL INC 1,677,546 5,318,000 0.21%
86 STREAMLINE HEALTH SOLUTIONS COM 2,272,759 5,205,000 0.20%
87 JAZZ INVESTMENTS I LTD 5,000,000 5,098,000 0.20% PRN
88 Catabasis Pharmaceuticals Inc 628,482 5,084,000 0.20%
89 SCYNEXIS INC 692,781 5,043,000 0.20%
90 Tracon Pharmaceuticals Inc 485,000 4,738,000 0.18%
91 Life Technologies Corp 461,530 4,735,000 0.18%
92 DERMA SCIENCES ORD 1,002,201 4,720,000 0.18%
93 STEADYMED LTD 1,315,169 4,669,000 0.18%
94 AKORN INCORPORATED 160,667 4,580,000 0.18%
95 Aldeyra Therapeutics Inc 690,538 4,026,000 0.16%
96 PENUMBRA INC COM 100,000 4,010,000 0.16%
97 CAS MED SYS INC 3,200,000 4,000,000 0.15%
98 BIODELIVERY SCIENCES INTL IN 700,000 3,892,000 0.15%
99 MIRATI THERAPEUTICS INC COM 110,049 3,788,000 0.15%
100 PSIVIDA CORP 972,110 3,548,000 0.14%
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Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001140361-15-041667, filed 2015.11.16).

From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.