| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ALDER BIOPHARMACEUTICALS INC | 1,689,071 | 42,176,000 | 5.98% | ||
| 2 | NEVRO CORP | 491,044 | 36,219,000 | 5.14% | ||
| 3 | HERON THERAPEUTICS INC | 1,771,263 | 31,971,000 | 4.53% | ||
| 4 | TESARO INC | 362,875 | 30,500,000 | 4.33% | ||
| 5 | NEKTAR THERAPEUTICS COM | 2,022,879 | 28,786,000 | 4.08% | ||
| 6 | MINERVA NEUROSCIENCES INC COM | 2,800,000 | 28,588,000 | 4.05% | ||
| 7 | Theravance Biopharma Inc | 1,118,372 | 25,376,000 | 3.60% | ||
| 8 | SAGE THERAPEUTICS | 730,000 | 21,995,000 | 3.12% | ||
| 9 | EAGLE PHARMACEUTICALS INC COM | 505,995 | 19,628,000 | 2.78% | ||
| 10 | MACROGENICS INC | 707,978 | 19,108,000 | 2.71% | ||
| 11 | VITAE PHARMACEUTICALS INC | 1,754,795 | 18,934,000 | 2.68% | ||
| 12 | GALAPAGOS NV | 334,044 | 18,347,000 | 2.60% | ||
| 13 | NEUROCRINE BIOSCIE COM USD0.001 | 398,301 | 18,103,000 | 2.57% | ||
| 14 | OMEROS CORP | 1,710,000 | 17,989,000 | 2.55% | ||
| 15 | ACLARIS THERAPEUTICS INC COM | 901,286 | 16,647,000 | 2.36% | ||
| 16 | PROTEOSTASIS THERAPEUTICS IN | 1,354,339 | 16,428,000 | 2.33% | ||
| 17 | Clearside Biomedical Inc | 1,988,208 | 13,937,000 | 1.98% | ||
| 18 | CELLECTIS S A | 498,117 | 13,245,000 | 1.88% | ||
| 19 | ARDELYX INC COM | 1,499,226 | 13,088,000 | 1.86% | ||
| 20 | CHINA BIOLOGIC PRODS INC | 112,867 | 12,000,000 | 1.70% | ||
| 21 | QUOTIENT LTD | 1,537,717 | 11,917,000 | 1.69% | ||
| 22 | SORRENTO THERAPEUTICS INC COM NEW | 2,121,013 | 11,878,000 | 1.68% | ||
| 23 | NOVAVAX INC COM | 1,619,608 | 11,775,000 | 1.67% | ||
| 24 | ALNYLAM PHARMACEUTICALS INC | 200,355 | 11,118,000 | 1.58% | ||
| 25 | COHERUS BIOSCIENCES INC COM | 576,106 | 9,730,000 | 1.38% | ||
| 26 | MYOKARDIA INC | 758,290 | 9,403,000 | 1.33% | ||
| 27 | PORTOLA PHARMACEUTICALS INC | 396,000 | 9,346,000 | 1.33% | ||
| 28 | DYNAVAX TECHNOLOGIES CORP | 635,000 | 9,258,000 | 1.31% | ||
| 29 | RELYPSA INC | 450,000 | 8,325,000 | 1.18% | ||
| 30 | WAVE LIFE SCIENCES LTD | 394,407 | 8,160,000 | 1.16% | ||
| 31 | SANGAMO BIOSCIENCES INCORPORATED | 1,402,331 | 8,119,000 | 1.15% | ||
| 32 | DEXCOM | 100,000 | 7,933,000 | 1.12% | ||
| 33 | ACHILLION PHARMACEUTICALS INC COM | 1,006,128 | 7,848,000 | 1.11% | ||
| 34 | INC Research Holdings Inc | 200,000 | 7,626,000 | 1.08% | ||
| 35 | SERES THERAPEUTICS INC | 253,064 | 7,352,000 | 1.04% | ||
| 36 | ADVAXIS INC COM NEW | 809,804 | 6,551,000 | 0.93% | ||
| 37 | AGENUS INC | 1,578,106 | 6,391,000 | 0.91% | ||
| 38 | SOCIETAL CDMO INC | 778,288 | 6,187,000 | 0.88% | ||
| 39 | FORWARD PHARMA A/S | 339,175 | 6,163,000 | 0.87% | ||
| 40 | CORBUS PHARMACEUTICALS HLDGS COM | 2,000,000 | 5,980,000 | 0.85% | ||
| 41 | ULTRAGENYX PHARMACEUTICAL INC COM | 110,842 | 5,421,000 | 0.77% | ||
| 42 | COLLEGIUM PHARMACEUTICAL INC COM | 455,515 | 5,398,000 | 0.77% | ||
| 43 | PFENEX INC COM | 632,559 | 5,295,000 | 0.75% | ||
| 44 | DERMIRA INC | 172,083 | 5,033,000 | 0.71% | ||
| 45 | ACCELERON PHARMA | 127,451 | 4,331,000 | 0.61% | ||
| 46 | Agile Therapeutics, Inc. | 563,880 | 4,291,000 | 0.61% | ||
| 47 | Atara Biotherapeutics Inc | 186,460 | 4,197,000 | 0.60% | ||
| 48 | Lion Biotechnologies | 505,941 | 4,098,000 | 0.58% | ||
| 49 | CYTOMX THERAPEUTICS INC COM | 371,636 | 3,796,000 | 0.54% | ||
| 50 | Intec Pharma Ltd | 809,804 | 3,724,000 | 0.53% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001140361-16-076682, filed 2016.08.15).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
