| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | INCYTE CORP | 23,498,460 | 1,702,933,000 | 17.96% | ||
| 2 | SEATTLE GENETICS INC | 43,235,267 | 1,517,126,000 | 16.00% | ||
| 3 | ALEXION PHARMACEUTIC | 6,542,599 | 910,861,000 | 9.61% | ||
| 4 | ABBVIE INC | 14,373,538 | 821,016,000 | 8.66% | ||
| 5 | ACADIA PHARMACEUTICALS INC COM | 24,213,838 | 677,019,000 | 7.14% | ||
| 6 | Incyte Corporation | 274,500,000 | 432,150,000 | 4.56% | PRN | |
| 7 | Incyte Corporation | 259,000,000 | 397,943,000 | 4.20% | PRN | |
| 8 | BIOMARIN PHARMACEUTICAL INC | 4,806,483 | 396,439,000 | 4.18% | ||
| 9 | GENOMIC HEALTH INC COM | 13,659,832 | 338,354,000 | 3.57% | ||
| 10 | Anacor Pharmaceuticals Inc | 5,122,375 | 273,791,000 | 2.89% | ||
| 11 | DBV TECHNOLOGIES S A | 5,509,560 | 179,336,000 | 1.89% | ||
| 12 | ACORDA THERAPEUTICS INC | 3,661,082 | 96,836,000 | 1.02% | ||
| 13 | BIOMARIN PHARMACEUTICAL INC SR SB CV1.875 17 | 22,379,000 | 89,825,000 | 0.95% | PRN | |
| 14 | CLOVIS ONCOLOGY INC | 129,300,000 | 87,801,000 | 0.93% | PRN | |
| 15 | GILEAD SCIENCES | 20,944,000 | 85,863,000 | 0.91% | PRN | |
| 16 | CERUS CORP | 13,553,275 | 80,371,000 | 0.85% | ||
| 17 | ANACOR PHARMACEUTICALS INC | 42,000,000 | 75,337,000 | 0.79% | PRN | |
| 18 | XENOPORT INC | 100,000,000 | 73,436,000 | 0.77% | PRN | |
| 19 | MIRATI THERAPEUTICS INC COM | 3,268,556 | 69,947,000 | 0.74% | ||
| 20 | ACORDA THERAPEUTICS INC | 77,083,000 | 68,456,000 | 0.72% | PRN | |
| 21 | AQUINOX PHARMACEUTICALS INC | 7,752,487 | 68,377,000 | 0.72% | ||
| 22 | INVITAE CORP | 6,554,967 | 67,057,000 | 0.71% | ||
| 23 | BEIGENE LTD | 1,912,680 | 56,061,000 | 0.59% | ||
| 24 | HERON THERAPEUTICS INC COM | 2,907,784 | 55,219,000 | 0.58% | ||
| 25 | BELLICUM PHARMACEUTICALS INCORPORATED | 4,865,647 | 45,494,000 | 0.48% | ||
| 26 | BIOCRYST PHARMACEUTICALS | 15,010,534 | 42,480,000 | 0.45% | ||
| 27 | IMMUNOGEN INC | 4,452,445 | 37,935,000 | 0.40% | ||
| 28 | SPARK THERAPEUTICS INCORPORATED | 1,262,382 | 37,253,000 | 0.39% | ||
| 29 | NEUROCRINE BIOSCIE COM USD0.001 | 895,422 | 35,414,000 | 0.37% | ||
| 30 | VERSARTIS INC | 3,199,559 | 25,660,000 | 0.27% | ||
| 31 | SANGAMO THERAPEUTICS INCORPORATED | 4,055,876 | 24,538,000 | 0.26% | ||
| 32 | ADVANCED ACCELERATOR APPLIC | 615,033 | 21,538,000 | 0.23% | ||
| 33 | Exelexis | 20,000,000 | 19,775,000 | 0.21% | PRN | |
| 34 | ACHILLION PHARMACEUTICALS IN | 2,475,515 | 19,111,000 | 0.20% | ||
| 35 | INSMED INC | 1,500,000 | 19,005,000 | 0.20% | ||
| 36 | Progenics Pharmaceuticals Inc | 4,350,808 | 18,970,000 | 0.20% | ||
| 37 | HALOZYME THERAPEUTICS INC | 1,931,057 | 18,287,000 | 0.19% | ||
| 38 | TG THERAPEUTICS INC COM | 2,003,991 | 17,074,000 | 0.18% | ||
| 39 | INTRA-CELLULAR THERAPIES INC | 609,166 | 16,935,000 | 0.18% | ||
| 40 | XENOPORT INC | 3,475,672 | 15,675,000 | 0.17% | ||
| 41 | MEDIVATION INC | 329,876 | 15,168,000 | 0.16% | ||
| 42 | BLUEBIRD BIO INC COM | 352,943 | 15,000,000 | 0.16% | ||
| 43 | FOAMIX PHARMACEUTICALS LTD | 2,241,702 | 14,616,000 | 0.15% | ||
| 44 | BIOMARIN PHARMACEUTICAL INC 0.75 10/15/2018 | 12,228,000 | 14,125,000 | 0.15% | PRN | |
| 45 | IDERA PHARMACEUTICALS INCORPORATED COM NEW | 6,990,189 | 13,841,000 | 0.15% | ||
| 46 | AEGERION PHARMACEUTICALS INC | 26,517,000 | 13,526,000 | 0.14% | PRN | |
| 47 | ARRAY BIOPHARMA INC | 4,310,666 | 12,716,000 | 0.13% | ||
| 48 | GALAPAGOS NV | 303,394 | 12,688,000 | 0.13% | ||
| 49 | AGIOS PHARMACEUTICALS INC | 307,915 | 12,501,000 | 0.13% | ||
| 50 | NOVAVAX INC COM | 2,379,254 | 12,277,000 | 0.13% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-16-102596, filed 2016.05.16).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
