| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | PROTHENA CORP PLC | 230,142 | 8,817,000 | 0.11% | ||
| 52 | THRESHOLD PHARMACEUTICAL INC | 1,826,358 | 8,693,000 | 0.11% | ||
| 53 | QLT INC | 1,535,863 | 8,539,000 | 0.11% | ||
| 54 | DISCOVERY LABORATORIES INC N | 3,652,117 | 7,852,000 | 0.10% | ||
| 55 | AGIOS PHARMACEUTICALS INC | 199,893 | 7,826,000 | 0.10% | ||
| 56 | GALECTIN THERAPEUTICS INC COM | 500,000 | 7,655,000 | 0.10% | ||
| 57 | INFINITY PHARMACEUTICALS INC | 624,050 | 7,420,000 | 0.09% | ||
| 58 | NEUROCRINE BIOSCIE COM USD0.001 | 447,874 | 7,211,000 | 0.09% | ||
| 59 | STEMLINE THERAPEUTICS INC | 338,671 | 6,895,000 | 0.09% | ||
| 60 | AMBIT BIOSCIENCES CORP | 747,954 | 6,821,000 | 0.09% | ||
| 61 | BIOTA PHARMACEUTIALS INC COM | 1,106,910 | 6,763,000 | 0.09% | ||
| 62 | ARRAY BIOPHARMA INC | 1,433,797 | 6,739,000 | 0.09% | ||
| 63 | ZOGENIX INC | 2,350,400 | 6,687,000 | 0.08% | ||
| 64 | IDERA PHARMACEUTICALS INCORPORATED COM NEW | 1,613,076 | 6,581,000 | 0.08% | ||
| 65 | XENCOR INC COM | 542,363 | 6,362,000 | 0.08% | ||
| 66 | AERIE PHARMACEUTICALS INC COM | 299,356 | 6,343,000 | 0.08% | ||
| 67 | NOVAVAX INC COM | 1,223,362 | 5,542,000 | 0.07% | ||
| 68 | IRONWOOD PHARMACEUTICALS INC | 446,160 | 5,497,000 | 0.07% | ||
| 69 | REGADO BIOSCIENCES INC | 400,000 | 5,008,000 | 0.06% | ||
| 70 | LIGAND PHARMACEUTICALS INC | 73,400 | 4,937,000 | 0.06% | ||
| 71 | ULTRAGENYX PHARMACEUTICAL INC COM | 100,000 | 4,889,000 | 0.06% | ||
| 72 | EPIZYME INC COM | 214,012 | 4,873,000 | 0.06% | ||
| 73 | OSIRIS THERAPEUTICS INC NEW COM | 361,530 | 4,747,000 | 0.06% | ||
| 74 | IGNYTA INC COM | 571,000 | 4,739,000 | 0.06% | ||
| 75 | PORTOLA PHARMACEUTICALS INC | 182,591 | 4,729,000 | 0.06% | ||
| 76 | CYTRX CORP | 1,350,000 | 4,712,000 | 0.06% | ||
| 77 | BLUEBIRD BIO INC COM | 198,260 | 4,508,000 | 0.06% | ||
| 78 | CELSUS THERAPEUTICS PLC | 673,887 | 4,374,000 | 0.06% | ||
| 79 | RETROPHIN INC | 197,178 | 4,194,000 | 0.05% | ||
| 80 | IONIS PHARMACEUTICAL | 96,303 | 4,161,000 | 0.05% | ||
| 81 | BIODELIVERY SCIENCES INTL IN | 421,005 | 3,553,000 | 0.05% | ||
| 82 | FURIEX PHARMACEUTICALS INC | 40,309 | 3,507,000 | 0.04% | ||
| 83 | ENANTA PHARMACEUTICALS INC | 80,957 | 3,237,000 | 0.04% | ||
| 84 | MACROGENICS INC | 96,165 | 2,676,000 | 0.03% | ||
| 85 | LA JOLLA PHARMACEUTICAL CO | 221,631 | 2,394,000 | 0.03% | ||
| 86 | SYNTA PHARMACEUTICALS CORP | 500,000 | 2,155,000 | 0.03% | ||
| 87 | MAST THERAPEUTICS INC COM | 3,000,000 | 2,040,000 | 0.03% | ||
| 88 | ORASURE TECHNOLOGIES INC | 234,664 | 1,870,000 | 0.02% | ||
| 89 | RIGEL PHARMACEUTICAL INC | 481,972 | 1,870,000 | 0.02% | ||
| 90 | KARYOPHARM THERAPEUTICS INC COM | 59,095 | 1,825,000 | 0.02% | ||
| 91 | AUXILIUM PHARMACEUTICALS INC | 58,544 | 1,591,000 | 0.02% | ||
| 92 | ACHAOGEN INC COM | 100,000 | 1,546,000 | 0.02% | ||
| 93 | ACHILLION PHARMACEUTICALS IN | 438,337 | 1,442,000 | 0.02% | ||
| 94 | OPHTHOTECH CORP | 36,776 | 1,314,000 | 0.02% | ||
| 95 | CATALYST PHARMACEUTICALS INC | 569,853 | 1,288,000 | 0.02% | ||
| 96 | ZIOPHARM ONCOLOGY INC | 244,619 | 1,120,000 | 0.01% | ||
| 97 | Receptos Inc | 23,900 | 1,002,000 | 0.01% | ||
| 98 | AMICUS THERAPEUTICS INC COM | 481,697 | 997,000 | 0.01% | ||
| 99 | ACCELERON PHARMA INC | 28,765 | 992,000 | 0.01% | ||
| 100 | TESARO INCORPORATED | 31,218 | 920,000 | 0.01% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-14-031196, filed 2014.05.15).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
